Exclusive Enteral Nutrition (EEN)

Exclusive Enteral Nutrition is primarily used to induce remission, particularly for pediatric Crohn's Disease (CD), as it has been studied extensively in this population. However, a likely potential benefit in ulcerative colitis (UC) has been suggested, and further research is recommended to evaluate its use in UC (Shaoul R et al). Exclusive Enteral Nutrition is often considered for use only in pediatric patients; however, a recent paper has shown it to be effective for inducing remission in adult patients with CD complicated with fistulas, abscesses, and strictures (Yang Q et al), and when used in the perioperative setting to avoid the need for surgery in some patients (Heerasing N et al). Although larger trials are needed to validate the use of EEN in these settings, there is potential for improved outcomes in complicated patients (Adamji M and Day AS). A publication by an Australian and New Zealand IBD working group provides recommendations for the use of EEN in active adult CD for the following clinical indications: induction of remission, as a bridge to medical therapy, preoperatively, and in the management of abdominal abscess or fistula (Day A et al). A recent review by Palchaudhuri S et al outlines the potential benefits of EEN and other dietary considerations for hospitalized patients.