Effectiveness of partial enteral nutrition to treat adults with Crohn's Disease who lost response to biological therapy.
PEN
For patients who lost response to biological therapy, the combination with PEN was associated with transmural response and clinical remission. Multiple failures to biologics were associated with adherence to PEN. Hence, the use of PEN dietary should be considered in difficult-to-treat patients
Journal of Crohn's and Colitis, Volume 17, Issue Supplement_1, February 2023, Pages i717–i718, https://doi.org/10.1093/ecco-jcc/jjac190.0719
Authors: Nardone O. et al.
P380 Changes in faecal microbiome and metabolome are more pronounced in Crohn’s disease patients who adhered to the CD-TREAT diet and responded by calprotectin
CD-TREAT
Treatment with the CD-TREAT solid food diet improves disease activity indices, faecal calprotectin (FCAL) levels and quality of life in adults and children with active Crohn’s disease (CD); particularly in patients who adhere to the diet. Here we describe changes in faecal microbiome parameters during therapy with CD-TREAT and explore these changes against adherence.
Journal of Crohn's and Colitis, Volume 17, Issue Supplement_1, February 2023, Pages i513–i515, https://doi.org/10.1093/ecco-jcc/jjac190.0510
Authors: Svolos V., et al.
Dietary Habit Modifications in Paediatric Patients after One Year of Treatment with the Crohn’s Disease Exclusion Diet
CDED
The participants demonstrated adequate adherence to the dietary regimen and their dietary patterns also improved. Although there are more factors influencing the course of this disease in these patients, improving their dietary habits is essential. To this end, maintaining a CDED under the supervision of a specialized dietitian is deemed an effective strategy.
Dietary Habit Modifications in Paediatric Patients after One Year of Treatment with the Crohn’s Disease Exclusion Diet. Nutrients 2023, 15, 554.
Authors: Martín-Masot R, et al.
Dietary adherence to the Mediterranean diet pattern in a randomized clinical trial of patients with quiescent ulcerative colitis
MED
Patients with UC can adhere to and tolerate the Mediterranean Diet Pattern (MDP) and achieve improved diet quality with reduced bowel symptoms compared to Canadian Habitual Diet (CHD). Increased adherence to the MDP can be achieved through appropriate support such as nutrition education and counseling by a Registered Dietitian. Overall, this data supports that the MDP can be recommended as a remission diet to UC patients to help support disease management alongside front-line therapy drugs.
Dietary adherence to the Mediterranean diet pattern in a randomized clinical trial of patients with quiescent ulcerative colitis. Frontiers in Nutrition, 9.
Authors: Haskey, N et al.
Lessons from an audit of exclusive enteral nutrition in adult inpatients and outpatients with active Crohn’s disease: a single-centre experience
EEN
Positive outcomes occur in 70% of adult patients with Crohn’s disease tolerating EEN and 81% in those who are able to completely adhere to EEN, without compromise of nutritional status. Similar success occurs when initiated as an inpatient or outpatient. Failure to tolerate EEN is the major hurdle to its use.
Lessons from an audit of exclusive enteral nutrition in adult inpatients and outpatients with active Crohn’s disease: a single-centre experienceFrontline Gastroenterology 2023;14:6-12.
Authors: Melton SL, et al
Successful Dietary Therapy in Paediatric Crohn's Disease is Associated with Shifts in Bacterial Dysbiosis and Inflammatory Metabotype Towards Healthy Controls
CDED
Successful dietary therapy induced correction of both compositional and functional dysbiosis. However, 12 weeks of diet was not enough to achieve complete correction of dysbiosis.
J Crohns Colitis. Published online September 15, 2022. doi: https://doi.org/10.1093/ecco-jcc/jjac105
Authors: Verburgt CM, et al.
Perspectives on Specific Carbohydrate Diet Education from Inflammatory Bowel Disease Patients and Caregivers: A Needs Assessment
SCD
Increasing educational content on the SCD to individuals, caregivers, and medical providers has the potential to improve adherence and sustainability on the SCD.
JPGN Reports. 2022;3(3):e222. doi: https://doi.org/10.1097/PG9.0000000000000222
Authors: Rivera, N. et al
Assessing Barriers to use of the Specific Carbohydrate Diet in Pediatric Inflammatory Bowel Disease: A Qualitative Study
SCD
To our knowledge, this is the first study examining barriers to the SCD among pediatric IBD patients.
JPGN Reports. 2022;3(3):e239
Authors: Schwartz N., et al.
Effect of the Crohn’s Disease Exclusion Diet (CDED) on the Fecal Calprotectin Level in Children with Active Crohn’s Disease
CDED
In their conclusion, the authors wrote: “In the group under analysis, this nutritional intervention resulted in a significant decrease in FCP level and contributed to normalization of this parameter in one-third of patients, which is a similar or better result compared to pharmacological treatment.”
J Clin Med. 2022;11(14):4146. doi: https://doi.org/10.3390/jcm11144146
Authors: Matuszczyk M, et al.
Photo Credit: Stock-Asso/Shutterstock
Personalized Research on Diet in Ulcerative Colitis and Crohn's Disease (PRODUCE): A Series of N-of-1 Diet Trials
SCD,
mSCD
“SCD and MSCD did not consistently improve symptoms or inflammation although some individuals may have benefited.”
Am J of Gastroenterol 2022 June 1;117(6):902-917.
Authors: Kaplan HC et al
Adherence to the Mediterranean Diet Improved Clinical Scores and Inflammatory Markers in Children with Active Inflammatory Bowel Disease: A Randomized Trial
MED
Adherence to the Mediterranean diet improves clinical scores and inflammatory markers in children and adolescents with mild-moderate active IBD.
J Inflamm Res. 2022;15:2075-2086. doi:10.2147/JIR.S349502
Authors: El Amrousy D, et al.
Photo Credit: Adisa/Shutterstock
Clinical and Histologic Remission in an Adult Crohn’s Disease Patient Following the Specific Carbohydrate Diet and Its Impact on Healthcare Costs
SCD
This case highlights the rapid and sustainable benefits of the SCD intervention in Crohn’s disease from both a clinical and economic standpoint.
Cureus 14(2): e22032. doi:10.7759/cureus.22032
Authors: Arjomand, A
