Food for Thought: Remission of Perianal Pediatric Crohn’s Disease on Specific Carbohydrate Diet Monotherapy
SCD
"We report a case with perianal and ileocolonic Crohn’s disease in whom SCD monotherapy successfully induced and maintained not only clinical, but also endoscopic, radiographic and histologic (ie, deep mucosal remission) remission as well."
JPGN Reports 4(3):p e343, August 2023. | DOI: 10.1097/PG9.0000000000000343
Authors: Simon D, MD, et al.
The Low FODMAP Diet for Children with Inflammatory Bowel Disease and Overlapping Functional Gastrointestinal Symptoms – a Case Series
Low-FODMAP
First case series to report on the short-term use of the Low-FODMAP diet in pediatric patients with quiescent IBD and functional GI symptoms.
Recent progress in Nutrition. 2023 juni, doi: 10.21926/rpn.2302009
Authors: Brown S. , et al.
P81 Identifying nutritional targets in Crohn’s disease: INTICO1: a time-limited trial of exclusive enteral nutrition during adult CD remission
EEN
"A time-limited trial (7 days) of EEN, given in this setting of adults in CD remission led to changes in micronutrient biochemistry, objective improvement in the bioelectrical properties of the body (increased phase angle) and an improvement in fatigue among the subjects as captured by the SF36-PF. The study suggests that impaired nutritional state and excessive fatigue is likely to be prevalent among adults with CD during remission and may be sensitive to nutritional intervention."
Gut 2023;72:A93.
Authors: Mcdonnell M, Westoby C, Sartain S, et al doi.org/10.1136/gutjnl-2023-BSG.153
Dietetic advocacy for long-term use of exclusive enteral nutrition resulted in high-risk surgical avoidance for complicated fibrotic Crohn's disease – A case report
EEN
The first case report of long-term use of EEN in a patient with complicated fibrotic Crohn's disease. "This unique case is a wonderful example of dietetic advocacy and showcases the positive impact long-term EEN may have on surgical avoidance, clinical outcomes and self-reported Quality of Life."
Clinical Nutrition ESPEN, Volume 57, 2023, Pages 1-4, ISSN 2405-4577,
Authors: Purcell L., et al.
A Mediterranean Diet Pattern Improves Intestinal Inflammation Concomitant with Reshaping of the Bacteriome in Ulcerative Colitis: A Randomised Controlled Trial
MED
An MDP induces gut microbiome alterations associated with the maintenance of clinical remission and reduced FC in patients with quiescent UC. The data support that the MDP is a sustainable diet pattern that could be recommended as a maintenance diet and adjunctive therapy for UC patients in clinical remission.
Journal of Crohn's and Colitis, 2023;, jjad073, https://doi.org/10.1093/ecco-jcc/jjad073
Authors: Haskey N. et al.
Effectiveness of partial enteral nutrition to treat adults with Crohn's Disease who lost response to biological therapy.
PEN
For patients who lost response to biological therapy, the combination with PEN was associated with transmural response and clinical remission. Multiple failures to biologics were associated with adherence to PEN. Hence, the use of PEN dietary should be considered in difficult-to-treat patients
Journal of Crohn's and Colitis, Volume 17, Issue Supplement_1, February 2023, Pages i717–i718, https://doi.org/10.1093/ecco-jcc/jjac190.0719
Authors: Nardone O. et al.
P380 Changes in faecal microbiome and metabolome are more pronounced in Crohn’s disease patients who adhered to the CD-TREAT diet and responded by calprotectin
CD-TREAT
Treatment with the CD-TREAT solid food diet improves disease activity indices, faecal calprotectin (FCAL) levels and quality of life in adults and children with active Crohn’s disease (CD); particularly in patients who adhere to the diet. Here we describe changes in faecal microbiome parameters during therapy with CD-TREAT and explore these changes against adherence.
Journal of Crohn's and Colitis, Volume 17, Issue Supplement_1, February 2023, Pages i513–i515, https://doi.org/10.1093/ecco-jcc/jjac190.0510
Authors: Svolos V., et al.
P499 Exclusive enteral nutrition induces transmural healing in adults with active Crohn’s disease
EEN
EEN was identified to induce early transmural response and healing in patients with active CD. Further studies are required to evaluate the capacity for EEN to induce transmural healing and the role of IUS as an early assessment tool in monitoring therapeutic response in CD.
Journal of Crohn's and Colitis, Volume 17, Issue Supplement_1, February 2023, Pages i628–i629
Authors: Chu M. et al.
Dietary Habit Modifications in Paediatric Patients after One Year of Treatment with the Crohn’s Disease Exclusion Diet
CDED
The participants demonstrated adequate adherence to the dietary regimen and their dietary patterns also improved. Although there are more factors influencing the course of this disease in these patients, improving their dietary habits is essential. To this end, maintaining a CDED under the supervision of a specialized dietitian is deemed an effective strategy.
Dietary Habit Modifications in Paediatric Patients after One Year of Treatment with the Crohn’s Disease Exclusion Diet. Nutrients 2023, 15, 554.
Authors: Martín-Masot R, et al.
Dietary adherence to the Mediterranean diet pattern in a randomized clinical trial of patients with quiescent ulcerative colitis
MED
Patients with UC can adhere to and tolerate the Mediterranean Diet Pattern (MDP) and achieve improved diet quality with reduced bowel symptoms compared to Canadian Habitual Diet (CHD). Increased adherence to the MDP can be achieved through appropriate support such as nutrition education and counseling by a Registered Dietitian. Overall, this data supports that the MDP can be recommended as a remission diet to UC patients to help support disease management alongside front-line therapy drugs.
Dietary adherence to the Mediterranean diet pattern in a randomized clinical trial of patients with quiescent ulcerative colitis. Frontiers in Nutrition, 9.
Authors: Haskey, N et al.
Lessons from an audit of exclusive enteral nutrition in adult inpatients and outpatients with active Crohn’s disease: a single-centre experience
EEN
Positive outcomes occur in 70% of adult patients with Crohn’s disease tolerating EEN and 81% in those who are able to completely adhere to EEN, without compromise of nutritional status. Similar success occurs when initiated as an inpatient or outpatient. Failure to tolerate EEN is the major hurdle to its use.
Lessons from an audit of exclusive enteral nutrition in adult inpatients and outpatients with active Crohn’s disease: a single-centre experienceFrontline Gastroenterology 2023;14:6-12.
Authors: Melton SL, et al
Successful Dietary Therapy in Paediatric Crohn's Disease is Associated with Shifts in Bacterial Dysbiosis and Inflammatory Metabotype Towards Healthy Controls
CDED
Successful dietary therapy induced correction of both compositional and functional dysbiosis. However, 12 weeks of diet was not enough to achieve complete correction of dysbiosis.
J Crohns Colitis. Published online September 15, 2022. doi: https://doi.org/10.1093/ecco-jcc/jjac105
Authors: Verburgt CM, et al.
