Low-Fat, High-Fiber Diet Reduces Markers of Inflammation and Dysbiosis and Improves Quality of Life in Patients With Ulcerative Colitis
Abstract
Fritsch, J., Garces, L., Quintero, M. A., Pignac-Kobinger, J., Santander, A. M., Fernández, I., Ban, Y. J., Kwon, D., Phillips, M. C., Knight, K., Mao, Q., Santaolalla, R., Chen, X. S., Maruthamuthu, M., Solis, N., Damas, O. M., Kerman, D. H., Deshpande, A. R., Lewis, J. E., … Abreu, M. T. (2021). Low-Fat, High-Fiber Diet Reduces Markers of Inflammation and Dysbiosis and Improves Quality of Life in Patients With Ulcerative Colitis. Clinical Gastroenterology and Hepatology, 19(6), 1189-1199.e30. https://doi.org/10.1016/j.cgh.2020.05.026
In a cross-over study of patients with UC in remission, we found that a catered LFD or iSAD were each well tolerated and increased quality of life. However, the LFD decreased markers of inflammation and reduced intestinal dysbiosis in fecal samples. Dietary interventions therefore might benefit patients with UC in remission.
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